Flunixin Meglumine CAS 42461-84-7 Stable supply

Product name: Flunixin Meglumine

MF: C21H28F3N3O7

MW: 491.46

CAS: 42461-84-7

EINECS: 255-836-0

Appearance: Off-white powder

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Application: Pharmacy

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Other name: Banamine (Veterinary); Flunixin N-methylglucanine; 2-(alpha(sup 3),alpha(sup 3),alpha(sup 3)-Trifluoro-2,3-xylidino)nicotinic acid compound with 1-deoxy-1-(methylamino)-D-glucitol (1:1); Finadyne; (2R,3R,4R,5S)-6-methylaminohexane-1,2,3,4,5-pentol; 2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]pyridine-3-carboxylic acid; 2-((2-Methyl-3-(trifluoromethyl)-phenyl)amino)-3-pyridinecarboxylic acid with meglumine compounded; D-Glucitol,1-deoxy-1-(methylamino)-,2-[[2- methyl-3-(trifluoromethyl)phenyl]amino]-3- pyridinecarboxylate (salt); 1-Deoxy-1-(methylamino)-D-glucitol 2-(2-methyl-3-(perfluoromethyl)anilino)nicotinate; 3-Pyridinecarboxylic acid, 2-((2-methyl-3-(trifluoromethyl)phenyl)amino)-, compd. with 1-deoxy-1-(methylamino)-D-glucitol (1:1); Flunixin Meglumine [USAN]; Banamine; 1-deoxy-1-(methylamino)-D-glucitol 2-[2-methyl-3-(perfluoromethyl)anilino]nicotinate; meglumine salt(Flunixin meglumine);

COA information

Testing items	Specifications	Results
Appearance	White to almost white, crystalline powder	Conforms
Solubility	Freely soluble in water and methanol, paractically insoluble in acetone	Conforms
Identification 1	Infrared absorption:197m;u ltraviolet absorption:197u	Conforms
Identification 2	Water: free soluble; ethanol(96%): free soluble Ethyl acetate: Practically insoluble	Conforms
Melting point	137~140℃	137.5~138.5
Ph	5 %(W/V)Water solution: 7.0~9.0	8.2
related substances	2-chloropyridine-3carboxylic acid ≤0.2%	Undetected
	2-methyl-3-(trifluoromethyl)aniline ≤0.2%	Undetected
	Ethyl 2-chloropyridine-3-carboxylate ≤0.2%	Undetected
	Ethyl 2-[[2-methyl-3-(trifluoromethyl) Phenyl]amino]pyridine-3-carboxylate ≤0.2%	Undetected
Impurities	1. Single impurity: not more than 0.2%	Conforms
	2. Unknown impurity: not more than 0.2%	Conforms
	Total impurities(1~2): not more than 0.5%	Conforms
Specific optical rotation	-9.0°~ -12.0°	-10.3°
Solvent residue	Isopropanol: not more than 0.5%	Conforms
	Ethanol: not more than 0.5%	Conforms
Bacterial endotoxins	Not more than 4.54 eu/mg	0.1 eu/mg
Loss on drying	≤0.5%	0.2%
Sulphated ash	≤0.1%	0.05%
Residue on ignition	≤0.2%	0.1%
Colour of solution	Clear,less coloured than reference solution y6,b.p.(vet)	Conforms
Clarification	1.2g funixin meglumine/8.8g water	Transparent
Explanation	Micronisarion 200±20um
Assay (hplc)	99.0~101.0%	99.64%
Conclusion	Comply with USP 37/EP7/BPV2012

Description

Flunixin Meglumine is a kind of veterinary medicine, can relieve muscle inflammation and pain caused by abnormal, relieve the horse’s visceral colic, the treatment of foal diarrhea, tremor, colitis, respiratory and other system diseases.

Application

Animal anti-inflammatory and analgesic drugs